| Dates of Office | Deputy Prime Minister | Political Affiliation |
| 16 Sep 1977 - 3 Jun 1979 | The Honourable Allan MacEachen | Liberal |
| 3 Jun 1979 - 3 Mar 1980 | Vacant |
|
| 3 Mar 1980 - 29 Jun 1984 | The Honourable Allan MacEachen | Liberal |
| 30 Jun 1984 - 16 Sep 1984 | The Honourable Jean Chrétien | Liberal |
| 17 Sep 1984 - 29 Jun 1986 | The Honourable Erik Nielsen | Progressive Conservative |
| 30 Jun 1986 - 24 Jun 1993 | The Honourable Don Mazankowski | Progressive Conservative |
| 25 Jun 1993 - 3 Nov 1993 | The Honourable Jean Charest | Progressive Conservative |
| 4 Nov 1993 - 30 Apr 1996 | The Honourable Sheila Copps | Liberal |
| 31 Apr 1996 - 18 Jun 1996 | Vacant |
|
| 19 Jun 1996 - 10 Jun 1997 | The Honourable Sheila Copps | Liberal |
| 11 Jun 1997 - 14 Jan 2002 | The Honourable Herb Gray | Liberal |
| 15 Jan 2002 - 11 Dec 2003 | The Honourable John Manley | Liberal |
| 12 Dec 2003 - 6 Feb 2006 | The Honourable Anne McLellan | Liberal |
| 6 Feb 2006 - | Vacant |
|